1. Female worms are ovoviviparous and can produce thousands of juveniles known as microfilariae, in infected humans. These are ingested by mosquitoes when they bite. The ingested microfilaria mature and eventually migrate to the insect proboscis from where they get injected into the human skin.
    en.wikipedia.org/wiki/Filariasis
    The vast majority of infected people are asymptomatic, but virtually all of them suffer from damages to the lymphatic system and the kidneys, and from an altered body's immune system. People infected with filariasis who have microfilaraemia or a positive antigen test should receive antifilarial drug treatment to eliminate microfilariae.
    www.who.int/health-topics/lymphatic-filariasis
    Lymphatic filariasis is a disease caused by microscopic parasitic worms. Most people have no symptoms, but in others it can cause arms, legs, breasts, or genitals to swell. Overview Lymphatic filariasis, sometimes called LF, is a disease caused by an infection with thread-like parasitic worms.
    www.cdc.gov/filarial-worms/about/lymphatic-filarias…
    Microfilariae develop in the mosquitoes. The transmission to dogs or other hosts including humans occurs through mosquito bite during subsequent blood meal. Humans may be infected as aberrant (accidental) hosts, mainly by D. repens and D. immitis. D. repens usually resides subcutaneously, while D. immitis frequently ends up in the human lung.
    europepmc.org/article/MED/24783097
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  6. Clinical Overview of Lymphatic Filariasis | Filarial …

    May 13, 2024 · Microfilariae can be detected microscopically on blood smears obtained at the time of peak microfilariae circulation (most often at night (10 PM – 2 AM). A thick smear should be made and stained with Giemsa or hematoxylin …

  7. Lymphatic filariasis - World Health Organization (WHO)

    Jan 30, 2020 · Lymphatic filariasis is a parasitic disease caused by three species of microscopic, thread-like worms. The adult worms only live in the human lymph system. The lymph system maintains the body's fluid balance and fights …

  8. Diagnostic Identification and Differentiation of …

    Sep 24, 2019 · Morphologic detection of microfilariae in blood or skin snips continues to be the gold standard for the routine clinical diagnosis of most human filariases. There are several important factors to consider when attempting an …

  9. Filariasis - StatPearls - NCBI Bookshelf

    Aug 8, 2023 · Microfilariae can be seen with a blood smear or other peripheral blood sample that is stained with either Giemsa or hematoxylin and eosin (H&E) stain. The blood samples should be taken after 8 pm.

  10. Lymphatic filariasis (Elephantiasis) - World Health …

    Oct 4, 2024 · Lymphatic filariasis is a parasitic disease that can result in an altered lymphatic system and the abnormal enlargement of body parts, causing pain, severe disability and social stigma. Infection occurs when filarial …

  11. Lymphatic Filariasis - Lymphatic Filariasis - MSD Manual Consumer …